Pointfest 26 was held on June 6, 2010 at Verizon Wireless Amphitheater. Hurt was originally scheduled to play but canceled due to illness. Autovein played in their place.
Main Stage
- Three Days Grace
- Seether
- Papa Roach
- Coheed & Cambria
- Saliva
Side Stages
- Hollywood Undead
- Story of the Year
- Janus
- Brookroyal
- Crash Kings
- Flobots
- Motion City Soundtrack
- Shaman's Harvest
- Greek Fire
- Autovein
- Jonathan Tyler and the Northern Lights
- Pop's Nightclub Winner: Opposites Attack
Pop's Local Stage
- Delta
- Inimical Drive
- Option Control
- Count the Lies
- Make Me Break Me
- Sonic Candy
- From Skies of Fire
- Killer Me Killer You
- Fivefold
- Break These Walls
- Breakdances with Wolves